With a URL to an OPeNDAP server, you can browse datasets, perform subset operations, and open your selected data directly in a tool you already use: R, Matlab, Xarray, IDL, Panoply, and more. (Wondering about a specific tool? Here’s a list of OPeNDAP-compatible client software.)
PyDAP, a pure python implementation of the DAP protocol (and a backend engine of Xarray), has a recent collection of examples demonstrating basic remote access and subset to OPeNDAP URLs.